HUBUNGAN ANTARA PROFIL KLINIS PADA HASIL GENERAL CHECK-UP PEGAWAI RSUP DR SARDJITO DENGAN HASIL PEMERIKSAAN KADAR ASAM URAT

ALFI KURNIA SARI, Prof.Dr.dr. Nyoman Kertia,Sp.PD-KR;dr. M. Robikhul Ikhsan, M.Kes, Sp.PD,KEMD

2016 | Skripsi | S1 PENDIDIKAN DOKTER

Latar Belakang: Prevalensi hiperurisemia terus meningkat. Profil klinis sepeti jenis kelamin, usia, indeks massa tubuh dan lingkar pinggang merupakan faktor risiko terjadinya hiperurisemia. Hiperurisemia merupakan salah satu faktor terjadinya penyakit gout, batu ginjal, kardiovaskular dan sindrom metabolik. Tujuan: Mengetahui hubungan antara profil klinis pada hasil general check-up pegawai RSUP Dr Sardjito dengan hasil pemeriksaan kadar asam urat. Metode: Penelitian ini menggunakan rancangan penelitian deskriptif analitik dengan mengkaji data sekunder dari hasil pemeriksaan General Check-Up pegawai RSUP DR Sardjito periode tahun 2014. Data disusun dan dianalisis tentang hubungan antara profil klinis meliputi jenis kelamin, usia, indeks massa tubuh(IMT), dan lingkar pinggang dengan kadar asam urat. Usia, lingkar pinggang dan indeks massa tubuh menggunakan uji korelasi Pearson dan Spearman sedangkan jenis kelamin menggunakan uji komparasi Mann-Whitney. Hasil: Berdasarkan hasil analisis komparasi Mann-Whitney, laki-laki cenderung memiliki kadar asam urat lebih tinggi dibanding perempuan dengan rerata peringkat laki-laki terhadap perempuan 235,1:207,79 (p=0,001). Hasil uji korelasi Pearson pada laki-laki menunjukkan IMT r=0,287;p<0,001, usia r=0,197;p=0,104 dan lingkar pinggang r=0,498;p=0,030. Pada perempuan menunjukkan IMT r=0,440;p<0,001, lingkar pinggang r=0,455;p=0,029 dan usia r=0,235;p<0,001 (korelasi Spearman). Simpulan: Penelitian terhadap 434 pegawai RSUP Dr Sardjito yang melakukan General Check-Up pada bulan Januari hingga Desember 2014 menunjukkan bahwa terdapat korelasi antara usia, indeks massa tubuh dan jenis kelamin dengan kadar asam urat. Jenis kelamin laki-laki, pertambahan usia dan kenaikan indeks massa tubuh akan meningkatkan kadar asam urat. Kata Kunci: profil klinis, usia, tinggi badan, berat badan, indeks massa tubuh, jenis kelamin, lingkar pinggang, asam urat, hiperurisemia, general check-up.

Background: The prevalence of hyperuricemia has risen nowadays. Clinical profile including sex, age, weight, height, body mass index and waist circumference are risk factors for the incidence of hyperuricemia. Hyperuricemia is one of factors of gout, renal calculi, cardiovascular disease and metabolic syndrome. Objective: The aim of this paper is to examine the correlation between clinical profile and uric acid from general check-up result of RSUP DR Sardjito Yogyakarta employees. Method: The study was a descriptive analytic utilizing secondary data of general check-up result. The data of all employee of RSUP DR Sardjito that have been examined from Januari to December 2014 were collected. Then the data including sex, age, body mass index and waist circumference examined to obtain its correlation with uric acid level. Age, waist circumference and body mass index were analyzed by using Pearson and Spearman correlation test while sex was by Mann-Whitney comparison’s. Results: Based on Mann-Whitney analysis results men have tendency to have uric acid level higher than women with ratio 235,1 vs 207,79(p=0,001) of mean. Pearson correlation test results among men were BMI (r=0,287;p<0,001), age(r=0,197;p=0,104) and waist circumference(r=0,498;p=0,030) while in women were BMI(r=0,440;p<0,001), waist circumference (r=0,455; p=0,029) and age(Spearman r=0,235;p<0,001). Conclusion: Research on 434 employees of RSUP DR Sardjito that have had general check-up examination on January to December 2014 shown that there were correlation between age, body mass index, and sex with uric acid level. Men, aged and higher body mass index have tendency to have higher level of uric acid. Keywords: clinical profile, age, heihgt, weight, body mass index, sex, waist circumference, uric acid, hyperuricemia, general check-up.

Kata Kunci : profil klinis, usia, tinggi badan, berat badan, indeks massa tubuh, jenis kelamin, lingkar pinggang, asam urat, hiperurisemia, general check-up.