RELATIONSHIP BETWEEN THE SEVERITY OF GASTRO ESOPHAGEAL REFLUX DISEASE ( GERD ) WITH ASTHMA CONTROL IN ASTHMATIC OUTPUT PATIENT IN RSUP DR. SARDJITO YOGYAKARTA

SOFIANSYAH YOSEF, dr.Heni Retnowulan, M.Kes, Sp.PD ; dr.Fahmi Indrarti, Sp.PD

2015 | Skripsi | PENDIDIKAN DOKTER

Latar Belakang: Asma Kontrol penting untuk penilaian dalam praktek klinis, meskipun bersifat multidimensi, ditandai dengan gejala, perubahan fungsi paru, dan efek pada kualitas hidup dan kemampuan fungsional. Penyakit refluks gastro esofageal didefinisikan sebagai gejala kerusakan mukosa pada kerongkongan karena masuknya isi lambung ke kerongkongan. Beberapa studi kasus pada pasien dengan gejala kronis gangguan saluran pernafasan atas menjelaskan adanya hubungan potensial antara saluran napas atas dan Penyakit Refluks Gastro Esofageal (PRGE). Metode: Desain penelitian studi ini adalah cross sectional dengan menggunakan Asma Kontrol Test (ACT) dan Gastro Esophageal Reflux Disease kuisioner (GERDQ). Berat lahir rendah ditelusuri secara retrospektif di masing-masing kelompok. Korelasi antara Asma Kontrol dan derajat keparahan PRGE dianalisis dengan menggunakan uji korelasi Pearson untuk signifikansi mereka. Kekuatan hubungan itu dinyatakan dalam koefisien korelasi (r). Nilai p-value kurang dari 0,05 dianggap signifikan secara statistik. Hasil: Asma yang tidak terkontrol ditemukan di 21 dari 32 pasien (65,6%) dan 5 dari 32 pasien dianggap sebagai PRGE yang berbeda secara statistik. r = -0.159, Cl95% = - 4,739-2,709 dan p = 0.384 Kesimpulan: Berdasarkan penelitian, tidak ada hubungan antara tingkat keparahan Penyakit Refluks Gastro Esofageal dengan Asma Kontrol.

Background: Asthma control is important to assess in clinical practice, although it is multidimensional in nature, characterized by symptoms, changes in pulmonary function, and effects on quality of life and functional ability. Gastro esophageal reflux disease is defined as symptoms or mucosal damage to the esophagus due to the entry of gastric contents into the esophagus. Several case studies of patients with chronic symptoms of upper respiratory tract disorders explains the potential relationship between upper airway and Gastro esophageal Reflux Disease (GERD). Method: The study design is a cross sectional study by using Asthma Control Test (ACT) and Gastro Esophageal Reflux Disease Questionnaire (GERDQ). The low birth weight was traced retrospectively in each group. The correlation between Asthma Control and GERD severity was analyzed by using Pearson Correlation Test for their significance. Strength of relationship was expressed in correlation coefficient(r). A p-value less than 0.05 were considered statistically significant. Result: Uncontrolled asthma was found in 21 of 32 patients (65,6%) and 5 of 32 patients was considered as GERD which were different statistically. r=-0,159, Cl95%=-4,739-2,709 and p=0,384 Conclusion: Based on the study, there is no relationship between the severity of gastro esophageal reflux disease and Asthma Control.

Kata Kunci : Asthma Control, Comorbidity, Gastro esophageal reflux disease, ACT, GERDQ