PROFILE OF EOSINOPHIL IN ASTHMATIC CHILDREN AT CHILD HEALTH DEPARTMENT DR.SARDJITO GENERAL HOSPIITAL

ROMZY AZMY LAZUARDI, dr. A. Roni Naning, M.Kes, Sp.A(K);dr. Amalia Setyati, Sp.A(K)

2014 | Skripsi | PENDIDIKAN DOKTER

Latarbekalang: Asma adalah salah satu penyakit inflamasi kronis pada saluran pernafasan. Secara umum, asma termasuk salah satu penyakit kronis paling sering yang menyerang lebih dari 300 juta jiwa. Lebih dari 80% kematian akibat asma muncul di negara berpenghasilan menengah-kebawah dan rendah. Prevalensi asma di Indonesia adalah 3,32% dimana Profinsi Gorontalo mencapai angka tertinggi 7,23% dan Nangroe Aceh Darussalam terendah 0,09%. Sedangkan di Jakarta memiliki prevalensi 2,94% dan penelitian serupa dilakukan pada siswa SD di Yogyakarta yang memperoleh prevalensi sebesar 4,8%. Tujuan: Untuk memperoleh profil eosinofil pada anak penderita asma sebagai karakteristik asma dan proporsi asma di RSUP Dr.Sardjito. Metode: Ini adalah penelitian observasional deskriptif, analisis, dan retrospektif. Data yang diambil berasal dari data sekunder berupa rekam medis di RSUP Dr.Sardjito. Metode sampling yang digunakan adalah accidental sampling. Tujuan dari penelitian ini untuk mengidentifikasi profil eosinofil asma pada anak. Data yang diperoleh akan dianalisis menggunakan metode deskriptif perbandingan dua proporsi dengan X 2 . Hasil: Data menunjukkan bahwa ada 69 pasien dengan angka eosinofil normal (83.13%) dan 14 pasien dengan peningkatan angka eosinofil (16.86%). Pada penelitian ini menunjukkan proporsi anak penderita asma di RSUP Dr.Sardjito sebesar 0.68%. Kesimpulan: Profil eosinofil pada pasien anak penderita asma yang dirawat inap sebagian besar normal. Proporsi asma diantara pasien rawat inap di RSUP Dr.Sardjito adalah 0.68%. Tidak ditemukan adanya hubungan antara jumlah eosinofil dan keparahan asma. Kunci: Asma, Anak, Eosinofil

Background: Asthma is one of the chronic inflammatory diseases of the respiratory track. Globally, as one of the most common chronic diseases, asthma has affected more than 300 million people. More than 80% deaths of asthma occured in lower-middle and low income countries. the prevalence of asthma in Indonesia was 3.32%, where Gorontalo province has the highest 7.23%, and Nangroe Aceh Darussalam is the lowest one (0.09%). While in the city of jakarta has a prevalence of 2.94%. The similar study conducted in Yogyakarta among elementary school student showed that the prevalence of asthma is 4.8%. Objective: To gain the profile of eosinophils in asthmatic children as the characteristic and th proportion of asthma in Dr.Sardjito General Hospital. Method: This study is descriptive observational, analytical and retrospective. The data are obtained from the secondary data by observing the child's medical records at Dr.Sardjito General Hospital. Sampling method in this study is the accidental sampling. This research is aimed at identifying the profile of eosinophils in asthmatic children. The Data will be analyzed by descriptive methods on the difference between two proportions using X 2 . Result: The data showed that there were 69 patients with normal eosinophil count (83.13%) and 14 patients with increased eosinophil count (16.86%). This study shows that the proportion of asthma in children at Dr.Sardjito General Hospital was 0.68%. Conclusion: the profile of eosinophils of hospitalized asthmatic children were mostly normal. The proportion of asthma among inpatient at Dr.Sardjito General Hospital was 0.68%. No correlation between eosinophil and asthma severity was identified. Keys: Asthma, Children, Eosinophils

Kata Kunci : Asma, Anak, Eosinofil,Asthma, Children, Eosinophils