PERBANDINGAN KUALITAS HIDUP PASIEN DISPEPSIA YANG MENGGUNAKANLANSOPRAZOLDENGAN INJEKSI RANITIDIN DI RSUD PANEMBAHAN SENOPATI BANTUL YOGYAKARTA

Okky Puspitasari S, dr. Probosuseno., SpPD., K-Ger

2014 | Tesis | S2 Mag.Farmasi Klinik

Dispepsia merupakan keluhan yang berhubungan dengan makan dan mencakup kualitas hidup pasien.Tujuan penelitian ini untuk mengetahui perbedaan kualitas hidup penderita dispepsia di RSUD Panembahan Senopati Bantul Yogyakarta yang mendapatkan terapi lansoprazol (2x30mg) atau injeksi ranitidin (2x25mg/ml) dengan menggunakan kuesioner kualitas hidup Nepean Dispepsia Indeks Indonesia (NDII). Metode penelitian adalah cross sectional dengan melakukan consecutive sampling selama periode April-Juni 2014. Data kualitas hidup dikumpulkan dari hasil pengisian kuesioner NDII saat pasien dirawat di Rumah Sakit.Analisa data dengan system skoring, chi-square, dan independent ttest. Subyek penelitian 30 pasien (masing-masing kelompok 15 responden). Hasil penelitian tidak ada perbedaan kualitas hidup antara pasien yang menggunakan injeksi ranitidine dengan lansoprazol pada keempat domain (p>0,05) (tension p=0,315), (aktivitas sehari-hari p=0,290), (makan/minum p=0,629), (pengetahuan/control p=0,698).

Dyspepsia is a complaint relating to eat and include the patient's quality of life. The purpose of this study was to determine differences in the quality of life of patients with dyspepsia at RSUD Panembahan Senopati Bantul Yogyakarta who received lansoprazole (2x30mg) or ranitidine injection (2x25mg / ml) by using a quality of life questionnaire Nepean Dyspepsia Index Indonesia (NDII). The method is a cross-sectional study with consecutive sampling done during the period April to June 2014, data were collected from the results of quality of life questionnaires NDII currently hospitalized patients. Analysis of the data with the scoring system, the chi-square and independent t-test. The subjects of the study 30 patients (each group of 15 respondents). The results of the study there was no difference in the quality of life among patients taking lansoprazole with ranitidine injection in four domains (p> 0.05) (p = 0.315 tension), (activities of daily p = 0.290), (eating / drinking p = 0.629) , (knowledge / control p = 0.698).

Kata Kunci : dyspepsia, lansoprazole, ranitidine injection, Nepean Dyspepsia Index