CORRELATION BETWEEN THYROID HORMONE PROFILE AND CLINICAL PRESENTATION OF PATIENT DIAGNOSED WITH HYPERTHYROIDISM IN SARDJITO HOSPITAL FROM JANUARY 2010-DECEMBER 2012.
FARA AMIRA BINTI ZAINUDIN, Dr. Mohammad Robikhul Ikhsan, Mkes., SpPD-KEMD.
2014 | Skripsi | PENDIDIKAN DOKTER-
Background : The most common form of hyperthyroidism is Graves disease, which also occurs seven to ten times more often in females than males, usually before age 40. Graves disease is an autoimmune disorder in which the person produces antibodies that mimic the action of thyroid-stimulating hormone (TSH). The antibodies continually stimulate the thyroid gland to grow and produce thyroid hormones. Objectives : To study what level of thyroid hormone profile will usually exhibit the clinical presentation of patients with hyperthyroidism. Method : This is a non-experimental research; it is an observational study using the retrospective method by viewing the medical record files of the research subjects. Medical record of the research subjects are traced back from January 2010 till December 2012 which have the code of ICD 10 : E05, hyperthyroidism. The data analysis was done in December 2013 using IBM SPSS 20. Result : Patients of hyperthyroidism (ICD 10: E05) may exhibit clinical manifestations of the signs and symptoms based on Waynes Index criteria, if the TSH (thyroid hormone profile) of them is less than the normal significant range; (0.49-4.67 uIU/ml), and if the FTâ‚„ (thyroid hormone profile) of them is more than the normal significant range; (0.71-1.85 ng/dl). Conclusion: Based on the results obtained, there is correlation between the clinical presentation of the hyperthyroid patients with the thyroid hormone profile for both FTâ‚„ and TSH level. Eventhough the xi data is insignificant with FTâ‚„ (P: 0.455) and TSH (P: 0.734), but the data is normal and valid to be included under the research.
Kata Kunci : FTâ‚„, TSH, Waynes Index.
