PENGARUH LATIHAN PASRAH DIRI TERHADAP PERBAIKAN DISFUNGSI EREKSI (Studi pada Penderita Gagal Ginjal Kronik dengan Simtom Depresi yang Menjalani Hemodialisis Rutin)

dr. Agus Susiloningsih, dr. Agus Siswanto, SpPD-Kpsi,

2012 | Tesis | S2 Ked.Klinik/MS-PPDS

Penderita gagal ginjal kronik (GGK) mengalami berbagai macam stresor fisik, psikis maupun sosial sehingga rentan terhadap munculnya simtom depresi. Simtom depresi dan berbagai kondisi yang terkait GGK pada penderita pria dapat menyebabkan terjadinya disfungsi ereksi. Latihan pasrah diri (LPD) merupakan bagian dari Complementary and Alternative Medicine (CAM) dalam penatalaksanaan simtom depresi yang memadukan relaksasi dan dzikir dengan fokus latihan pada pernafasan dan kata yang terkandung didalam dzikir (relaxation and repetitive prayer) untuk membangkitkan respons relaksasi, sehingga diharapkan mampu memperbaiki gejala stres ataupun simtom depresi. Tujuan penelitian ini untuk mengetahui pengaruh LPD terhadap perbaikan simtom depresi dan disfungsi ereksi pada penderita gagal ginjal kronik dengan simtom depresi. Penelitian menggunakan metode Randomized Placebo Controlled Trial (RCT) yang dilakukan di Unit Hemodialisis RSUP Dr. Sardjito antara bulan Januari sampai Mei 2012. Distribusi atau sebaran data diuji dengan menggunakan uji statistik Shapiro-Wilk. Perbedaan skor rerata BDI dan skor rerata IIEF-5 masing-masing kelompok dengan uji t untuk kelompok berpasangan jika distribusinya normal atau Wilcoxon test jika distribusi tidak normal. Pengaruh LPD terhadap perbedaan skor rerata BDI dan skor rerata IIEF kelompok perlakuan dibanding kontrol diuji dengan independent t-test. Perbedaan dianggap bermakna bila nilai p< 0,05 dengan interval kepercayaan 95 %. Hasil penelitian menyajikan karakteristik subyek berdasarkan umur, jenis kelamin, tingkat pendidikan, pekerjaan, status merokok, IMT, penyakit komorbid, terapi, profil lipid, kadar ureum dan kreatinin, hemoglobin, fungsi hati, skor BDI dan skor IIEF-5. Penelitian ini akan menunjukkan manfaat LPD terhadap perbaikan simtom depresi dan disfungsi ereksi penderita GGK yang menjalani hemodialisis rutin.

Patients with chronic renal failure (CRF) had both of physical, psychological and social stressors, so vulnerable to the emergence of depression symptoms. Symptoms of depression and other conditions related to CRF lead to erectile dysfunction in male patients. “Latihan Pasrah Diri (LPD)” is a part of the Complementary and Alternative Medicine (CAM) in the management strategies of depression symptoms that combines relaxation and “dhzikr’ (repetitive prayer) focusing on breathing and the words contained in the “dhzikr’ to evoke the relaxation response, which expected to improve the depression symptoms. This study was conducted to determine the effect of LPD on the improvement of symptoms of depression and erectile dysfunction on hemodialysis patients with symptoms of depression. A Randomized Placebo Controlled Trial (RCT) design was conducted in the Hemodialysis Unit of Dr. Sardjito hospital between January and May 2012. Data distribution was tested using Shapiro-Wilk statistical test. The Beck Depression Inventory (BDI) mean score and the IIEF-5 mean score difference of each group was tested by t-test for paired group if the distribution of data was normal or Wilcoxon test if the distribution was not normal. Effect of LPD on BDI mean score and the IIEF-5 mean score differences of the treatment and control groups were tested using independent t-test. The differences were significant if p value <0.05 with 95% confidence of interval. The results of this study were present the characteristics of subjects by age, sex, educational level, occupation, smoking status, BMI, comorbids, therapy, lipid profile, blood urea and creatinine, hemoglobin, liver function, BDI score and IIEF-5 score. This research will demonstrate the benefits of LPD on the improvement of depression symptoms and erectile dysfunction on hemodialysis patients.

Kata Kunci : GGK, LPD, simtom depresi, disfungsi ereksi