EVALUASI PENGGUNAAN ANTI BIOTIKA PRE DAN POST OPERATIF PADA TINDAKAN PEMBEDAHAN DI BANGSAL BEDAH INSTALASI RAWAT INAP RUMAH SAKIT UMUM DAERAH ULIN BANJARMASIN PERIODE SEPTEMBER-NOPEMBER 2006

Sulistyaningtyas Atmini Handayani, Apt, Prof. Dr. Zullies Ikawati, Apt.

2011 | Tesis | S2 Mag.Farmasi Klinik

bakteri, reaksi hipersensitivitas, superinfeksi dan Ketidak tepatan pemberian antibiotika pada kasus pembedahan akan meningkatkan resistensi memperpanjang masa perawatan (Setiawan, 2003). Penelitian ini bertujuan untuk mengevaluasi penggunaan antibiotika pre operatif dan post operatif pada tindakan pembedahan di bangsal Instalasi Rawat Inap RRUD Ulin Banjarmasin. Treatment Guidelines From The Medical Letter Penelitian ini merupakan penelitian non eksperimental dengan rancangan deskriptif evaluatif melalui penelusuran data secara prospektif terhadap rekam medik pasien rawat inap RSUD Ulin Banjarmasin periode September – Nopember 2006. Permasalahan yang akan dievaluasi adalah kesesuaian pemilihan antibiotika baik pre dan post operatif dengan Standar Pelayanan Medik bagian Bedah dan , (2009) serta Antibiotic Prophylaxis in Surgery (SIGN, 2008), kesesuaian dosis, cara dan lama pemberian dengan Drug Information Handbook (2011-2012) serta efektivitas penggunaan antibiotika. Antibiotika pre dan post operatif yang banyak digunakan Cefotaxim 1 gr (32 dan 25 k Karakteristik 95 pasien (75 orang laki laki, 20 orang perempuan), usia terbanyak 16-60 tahun (49 orang), operasi kotor (59 orang), operasi elektif (67 orang), operasi kurang dari 1 jam (74 orang). asus). Kesesuaian dengan Standar Pelayanan Medik pada pre operatif 65 kasus (68,24%) dan pada post operatif 63 kasus (66,31%), sedangkan dosis, cara dan lama pemberian yang sesuai dengan Drug Information Handbook (2011-2012) pada pre operatif 54 kasus (56,84%) dan pada post operatif 46 kasus (48,42%). Kesesuaian dengan Treatment Guidelines From The Medical Letter, (2009) serta Antibiotic Prophylaxis in Surgery (SIGN, 2008), pada pre operatif 58 kasus (61,05%) dan post operatif 59 kasus (62,11%), sedangkan dosis, cara dan lama pemberian yang sesuai dengan Drug Information Handbook (2011-2012) pada pre operatif 48 kasus (50,53%) dan pada post operatif 42 kasus (44,21%). Efektivitas penggunaan antibiotika pre operatif lebih baik pada yang tidak sesuai Standar Pelayanan Medik maupun Treatment Guidelines From The Medical Letter, (2009) serta Antibiotic Prophylaxis in Surgery (SIGN, 2008) dengan kasus infeksi hanya 7 pasien (7,39%). Treatment Guidelines From The Medical Letter, (2009) Kesesuaian penggunaan lebih tinggi dengan Standar Pelayanan Medik dari pada dengan baik pada pre operatif maupun post operatif, kejadian infeksi masih tinggi (38 orang) dan meninggal 2 orang.

Inaccurate administration of antibiotics in surgical cases will increase bacterial resistance, hypersensitivity reactions, superinfection and extend the maintenance period (Setiawan, 2003). This study aims to evaluate the use of antibiotics pre operative and post operative surgery on the ward Ward District General Hospital Ulin Banjarmasin. Treatment Guidel This research is a non-experimental research design with descriptive evaluative data prospectively through a search of medical records of inpatients Hospital Ulin Banjarmasin period September - November 2006. Issues to be evaluated is the suitability of antibiotic selection both pre and post operative with the Standards of Medical Care Surgery and ines From The Medical Letter, (2009) as well as Antibiotics Prophylaxis in Surgery (SIGN, 2009), the appropriateness of dosage, method and duration of the Drug Information Handbook (2011-2012) as well as the effectiveness of the use of antibiotics. Treatment Guidelines From The Medical Letter, (2009) Characteristics of 95 patients (75 men, 20 women), aged 16-60 years most (49 people), dirty operation (59 people), elective operation (67 people), the operation is less than 1 hour (74 people). Pre and post operative antibiotics are widely used Cefotaxim 1 g (32 and 25 cases). Compliance with the Standards of Medical Care in the pre operative 65 cases (68.24%) and post-operative in 63 cases (66.31%), while the dosage, method and duration of in accordance with the Drug Information Handbook (2011-2012) on 54 cases of pre-operative (56.84%) and post-operative in 46 cases (48.42%). Conformity with as well as antibiotics Prophylaxis in Surgery (SIGN, 1999) in pre operative 58 cases (61.05%) and post-operative 59 cases (62.11%), while the dose, how and duration of which in accordance with the Drug Information Handbook (2011-2012) on the pre operative 48 cases (50.53%) and on post-operative 42 cases (44.21%). The effectiveness of pre-operative use of antibiotics is better in an inappropriate or Treatment Guidelines From The Medical Letter, (2009) as well as Antibiotics Prophylaxis in Surgery (SIGN, 2009) with only 7 cases of infection patients (7.39%). Treatment Guidelines From The Medical Letter, (2009) Compliance is higher with the use of Standards of Medical Care in the as well as Antibiotics Prophylaxis in Surgery (SIGN, 2009) both at the pre operative and post operative, incidence of infection is still high (38 persons) and died 2 people.

Kata Kunci : antibiotika pre operatif, antibiotika post operatif, infeksi luka operasi.