Laporkan Masalah

Determinan pengendalian tuberkulosis melalui implementasi pemberian terapi pencegahan tuberkulosis pada kontak serumah di Kabupaten Kebumen tahun 2025

Yunianti, dr. Nur Rahmi Ananda, SpPD, Subs.P.M.K.(K)

2026 | Tesis | S2 Ilmu Kesehatan Masyarakat

Latar Belakang:  Indonesia adalah salah satu dari 30 negara dengan beban tuberkulosis tertinggi dan secara kolektif menyumbang 87?ri kasus global. Sebagai upaya mencapai eliminasi tahun 2030, pemerintah menetapkan beberapa indikator program. Salah satu indikator tersebut adalah pemberian terapi pencegahan tuberkulosis pada kontak serumah. Namun, dalam beberapa tahun terakhir, indikator tersebut belum mencapai target.

Tujuan: Penelitian ini bertujuan untuk mengevaluasi implementasi pemberian terapi pencegahan tuberkulosis serta mengidentifikasi faktor-faktor yang memengaruhi penerimaan terapi pencegahan tuberkulosis pada kontak serumah

Methods: Penelitian terdiri atas 3 sub-studi, yaitu evaluasi program, evaluasi sistem surveilans, dan studi analitik. Evaluasi program dan evaluasi sistem surveilans menggunakan metode deskriptif observasional, sedangkan studi analitik menggunakan metode mixed-methods explanatory sequential study. Data primer dikumpulkan melalui wawancara menggunakan kuesioner dan penelusuran dokumen. Total sampel untuk evaluasi program dan evaluasi surveilans adalah 48 responden. Sedangkan total sampel pada studi analitik adalah 389 dengan teknik proportional stratified random sampling.   

Hasil: Capaian pemberian terapi pencegahan tuberkulosis di Kabupaten Kebumen meningkat setiap tahun, tetapi belum mencapai target. Kendala program meliputi keterbatasan logistik, pembiayaan yang belum memadai, pelatihan pengelola program yang belum merata, serta pelaksanaan investigasi kontak dan rujukan yang belum optimal. Seluruh unit pelapor telah menggunakan SITB dalam permintaan logistik, namun kualitas pencatatan belum sepenuhnya menggambarkan seluruh alur layanan TPT. Faktor yang secara signifikan berhubungan dengan penerimaan terapi pencegahan tuberkulosis adalah menerima informasi terkait terapi pencegahan tuberkulosis dari kader (aPR=1,12; 95% CI 1,01–1,25), responden yang menerima informasi dari tenaga kesehatan  (aPR=1,09; 95% CI 1,00–1,19), etikal (aPR=1,64; 95% CI 1,12–2,39), koherensi intervensi (aPR=0,87; 95% CI 0,79–0,97), efikasi diri (aPR=2,16; 95% CI 1,38–3,37)

Kesimpulan: Capaian pemberian terapi pencegahan tuberkulosis mengalami peningkatan, tetapi masih memerlukan peningkatan terutama pada  ketersediaan logistik,  kapasitas pengelola program,  investigasi kontak dan edukasi masyarakat.

 

Kata kunci:  Terapi pencegahan tuberkulosis, Kontak serumah, Tuberkulosis, Pengendalian  tuberkulosis


Background: Indonesia is one of the 30 countries with the highest tuberculosis burden, collectively accounting for 87% of global cases. In an effort to achieve elimination by 2030, the government has established several program indicators. One of these indicators is the provision of tuberculosis preventive therapy to household contacts. However, in recent years, this indicator has not met its target.
Objective: This study aims to evaluate the implementation of tuberculosis preventive therapy and identify factors influencing the acceptance of tuberculosis preventive therapy among household contacts.

Methods: The study consists of three sub-studies: a program evaluation, a surveillance system evaluation, and an analytical study. The program evaluation and surveillance system evaluation employed descriptive observational methods, whereas the analytical study utilized a mixed-methods explanatory sequential study design. Primary data were collected through interviews, questionnaires, and document reviews. The total sample size for the program evaluation and surveillance evaluation was 48 respondents. Meanwhile, the total sample size for the analytical study was 389, which was determined using proportional stratified random sampling.

Results: The uptake of tuberculosis preventive therapy in Kebumen Regency has increased annually, but has not yet reached the target. Program constraints include logistical limitations, inadequate funding, uneven training of program managers, and suboptimal implementation of contact tracing and referrals. All reporting units have used the SITB system for logistics requests; however, the quality of record-keeping does not yet fully reflect the entire TPT service pathway. Factors significantly associated with the acceptance of tuberculosis preventive therapy include receiving information about tuberculosis preventive therapy from community health workers (aPR=1.12; 95% CI 1.01–1.25), respondents who received information from health workers  (aPR = 1.09; 95% CI 1.00–1.19), and ethical considerations (aPR = 1.64; 95% CI 1.12–2.39), intervention coherence (aPR = 0.87; 95% CI 0.79–0.97), and self-efficacy (aPR = 2.16; 95% CI 1.38–3.37)
Conclusion: The implementation of tuberculosis preventive therapy has improved, but further improvements are still needed, particularly in  logistical availability,  program management capacity,  contact tracing, and community education.

Keywords: Tuberculosis preventive therapy, Household contacts, Tuberculosis, Tuberculosis control

Kata Kunci : Keywords: Tuberculosis preventive therapy, Household contacts, Tuberculosis, Tuberculosis control

  1. S2-2026-536737-abstract.pdf  
  2. S2-2026-536737-bibliography.pdf  
  3. S2-2026-536737-tableofcontent.pdf  
  4. S2-2026-536737-title.pdf