Pengaruh Agen Remineralisasi Biomimetik Nanospray CMC/ACP Cangkang Achatina fulica dan Minyak Atsiri Zingiber officinale var. rubrum Terhadap Kekasaran Permukaan Dentin

Tiara Ayu Fitrah Haida, Dr.drg. Archadian Nuryanti, M.Kes.; Dr. drg. Anne Handrini D., M.Kes.

2025 | Skripsi | PENDIDIKAN DOKTER GIGI

Gigi sensitif dapat menyebabkan psikologis seseorang terganggu dikarenakan proses demineralisasi. Beberapa bahan alami seperti cangkang Achatina fulica digunakan sebagai ACP. Bahan tersebut dikombinasikan CMC dari kitosan dan minyak atsiri Zingiber officinale var. rubrum sebagai agen remineralisasi biomimetik. Tujuan penelitian ini untuk mengetahui pengaruh nanospray CMC/ACP cangkang Achatina fulica dan minyak atsiri Zingiber officinale var. rubrum terhadap kekasaran permukaan dentin.

Total subjek penelitian adalah 27 (n=3 untuk setiap kelompok durasi dan jenis perlakuan). Pengukuran kekasaran permukaan dentin dilakukan sebelum remineralisasi (demineralisasi dengan asam sitrat 6%) dan setelah remineralisasi. Jenis perlakuan remineralisasi terdiri atas 3 jenis (nanospray kontrol negatif tanpa ACP, nanospray CMC/ACP cangkang Achatina fulica dan minyak atsiri Zingiber officinale var. rubrum, Pepsodent Sensitive Mineral Expert sebagai kontrol positif). Pengukuran kekasaran permukaan dentin dilakukan menggunakan surface roughness tester.

Hasil uji Two-Way ANOVA menunjukkan bahwa durasi serta jenis perlakuan berpengaruh terhadap kekasaran permukaan dentin oleh nanospray CMC/ACP cangkang Achatina fulica dan minyak atsiri Zingiber officinale var. rubrum. Hasil LSD menunjukkan bahwa terdapat beberapa perbedaan signifikan antara nanospray CMC/ACP cangkang Achatina fulica dan minyak atsiri Zingiber officinale var. rubrum dengan kontrol positif dalam kekasaran permukaan dentin. Kesimpulan penelitian ini adalah agen remineralisasi biomimetik nanospray CMC/ACP cangkang Achatina fulica dan minyak atsiri Zingiber officinale var. rubrum berpotensi menurunkan kekasaran permukaan dentin. 

Sensitive teeth can cause psychological disturbances due to the demineralization process. Several natural ingredients, such as Achatina fulica shells are suitable for use as ACP. This material is combined with CMC from chitosan and Zingiber officinale var. rubrum essential oil as a biomimetic remineralization agent. The purpose of this study was to determine the effect of CMC/ACP nanospray from Achatina fulica shells and Zingiber officinale var. rubrum essential oil on dentin surface roughness.

A total of 27 subjects participated (n=3 for each treatment duration and type). Dentin surface roughness measurements were performed before and after remineralization (demineralization with 6% citric acid). The remineralization treatments consisted of three types (a negative control nanospray without ACP, a CMC/ACP nanospray of Achatina fulica shells and Zingiber officinale var. rubrum essential oil, and Pepsodent Sensitive Mineral Expert as a positive control). Dentin surface roughness was measured using a surface roughness tester.

The Two-Way ANOVA test results showed that the duration and the type of treatment affected dentin surface roughness by the CMC/ACP nanospray of Achatina fulica shells and Zingiber officinale var. rubrum essential oil. The LSD results showed that there were several significant difference between the CMC/ACP nanospray of Achatina fulica shells and Zingiber officinale var. rubrum essential oil and the positive control in dentin surface roughness. The conclusion of this study is that the biomimetic remineralization agent CMC/ACP nanospray from Achatina fulica shell and Zingiber officinale var. rubrum essential oil has the potential to reduce dentin surface roughness. 

Kata Kunci : remineralisasi biomimetik, CMC/ACP, Achatina fulica, Zingiber officinale var. rubrum, kekasaran permukaan