Pengaruh infus batang tabat barito (Ficus deltoidea Jack.) terhadap kadar Progresteron dan kapasitas reproduksi Mencit (Mus musculus L.)

KARIM, Aditya Krishar, Drs. Suharno, SU

2005 | Tesis | S2 Biologi

Tabat Barito (Ficus deltoidea Jack.) bersifat afrodisiak dan berpengaruh terhadap organ reproduksi betina. Penelitian ini bertujuan untuk mengkaji pengaruh infus batang tabat barito terhadap konsentrasi hormon progesteron dan kapasitas reproduksi mencit betina. Tiga puluh ekor mencit betina dibagi secara acak ke dalam 5 kelompok. Dosis perlakuan yaitu kontrol, plasebo, dosis 50 %, 75% dan 100%. Infus dan akuades diberikan pada mencit per oral sebanyak 0.5 ml/hari selama 5 siklus estrus. Tiga ekor mencit betina diambil darahnya untuk pengukuran konsentrasi progesteron dengan metode RIA. Tiga ekor lainnya dikawinkan. Pada 18 hari kebuntingan mencit dibedah. Variabel yang diamati meliputi berat induk, berat basah uterus, berat basah hati, jumlah anak, rerata panjang dan berat anak. Data dianalisa dengan Anova dan dilanjutkan dengan uji DMRT. Hasil dari penelitian ini menunjukkan bahwa ada perbedaan antara kontrol dan perlakuan pada konsentrasi progesteron. Pada kontrol konsentrasi lebih rendah daripada perlakuan, sedangkan konsentrasi tertinggi yaitu pada perlakuan dosis 75%. Dari hasil ini menunjukkan bahwa infus tabat barito menyebabkan peningkatan konsentrasi progesteron namun tidak signifikan (p>0.05), selain itu juga menyebab kan peningkatan kapasitas reproduksi.

Tabat barito (Ficus deltoidea Jack.) is vastly used to induce sexual aroused (aphrodisiacs,) and affect female reproductive organ. The aim of this research was performed to examine the effects of tabat barito on progesterone concentration and reproductive capacities of female mice. Thirty female mice were devided randomly into 5 groups of 6, respectively. The treatment dosages were control, placebo, 50%, 75% and 100%. Infuse and aquades administrated orally for 5 estrouse cycles. Three female mice were sacrificed to get their blood samples for progesterone analysis using RIA method. The others mice were mated. At the eighteen days of gestation, female mice were sacrificed and observed, covered the weight of mice, uterus, liver; the total number of fetus, their weight and length body. The statistical analysis was performed using ANOVA and DMRT. The result of this study indicated that there was distinction between control and treatment on progesterone concentration. In control, concentration was lower than treatment. Whereas, the highest concentration was in treatment with dosage 75%. The result showed that tabat barito infuse treatment on female mice caused increasing progesterone concentration but it was not significant (p>0.05), it also caused increasing female reproductive capacities.

Kata Kunci : Biologi Hewan,Tabat Barito,Kapasitas Reproduksi,Progesteron, Tabat Barito, Aphrodisiacs, Progesterone, Reproductive capacities