TROBOSITOPENIA DENGAN HASIL SEROLOGIS PENDERITA DEMAM BERDARAH DENGUE RAWAT INAP DI RSUP DR. SARDJITO

Harakati Wangi, dr. Soebagyo Loehoeri, SpPD, DAP&E ; dr. Wahyu Danawati

1998 | Skripsi | S1 KEDOKTERAN

Dengue Hemorrhagic Fever (DHF) is an important publica health problem in South East Asian and Western Pacific countries and is one of the leading causes in hospitalization. A descriptive analytic study using Pearson’s chi-square test was conducted to evaluate the association between thrombocytopenia and the serologic results. All patients hospitalized in the Department of Internal Medicine DR. Sarddjito General Hospital, Yogyakarta with DHF diagnosed based on WHO 1986 criteria and fulfills the inclusion and exclusion criteria was studied retrospectively. Data is presented in percentage by frequency of age, sex, serologic results and thrombocytopenia (defined if the platelet count less than 100.000/ml). Ninty three patients found with the range of age were 14 to more than 53 years old who fulfilled the criteria were evaluated. Of 93 cases, they were 53 (57%) men and 40 (43%) women and statistically not difference (men: women = 1,3 : 1). The largest number of patients were among the age of 14 to 21 years old (62,1%). Eighty seven (95,3,5%) patients showed positive serologic results and 6 (6,5%) patients with negative results. Thrombocytopenia occurred in 70,65% of DHF positif serologic results and 57,69% of serologic negative. The statistical test was X2 = 4.17364 with p<0.05. It is concluded there was a fignificant difference in thrombocytopenia between the serologic positive and negative results.

Kata Kunci : Dengue Hemorrhagic Fever, thrombocytopenia