Formulasi Krim Berbasis Minyak Tamanu dengan Variasi Konsentrasi Ekstrak Licorice serta Uji Stabilitas Fisik, Aktivitas Antioksidan dan Perlindungan UV
Widya Nur Jannah, Dra. Ani Setyopratiwi, M.Si. ; Akhmad Syoufian, S.Si., Ph.D.
2025 | Skripsi | KIMIA
Telah
dilakukan penelitian mengenai formulasi krim berbasis minyak tamanu dengan
variasi konsentrasi ekstrak licorice serta uji stabilitas fisik, aktivitas
antioksidan, dan perlindungan UV. Tujuan penelitian ini adalah membuat dan
melakukan karakterisasi sediaan krim berbahan dasar minyak tamanu, mempelajari
pengaruh variasi penambahan ekstrak licorice terhadap stabilitas fisik sediaan
krim, serta mengetahui aktivitas antioksidan dan nilai SPF dalam krim berbahan
dasar minyak tamanu dengan variasi penambahan ekstrak licorice. Penelitian ini
diawali dengan uji karakteristik minyak tamanu meliputi kadar air, asam lemak
bebas, dan bilangan peroksida. Sediaan krim dibuat tanpa ekstrak licorice dan
dengan penambahan ekstrak licorice konsentrasi 1%, 2%, dan 3%. Parameter uji
stabilitas fisik sediaan krim meliputi uji organoleptis, pH, homogenitas, daya
sebar, pemisahan fase, ukuran droplet, dan tipe emulsi. Uji aktivitas
antioksidan dan nilai Sun Protection Factor (SPF) dilakukan menggunakan
spektrofotometer UV-Vis.
Hasil penelitian menunjukkan bahwa penambahan ekstrak licorice memengaruhi stabilitas fisik krim. Peningkatan konsentrasi ekstrak licorice menurunkan nilai pH, daya sebar, serta ukuran droplet sediaan krim. Sedangkan aktivitas antioksidan dan nilai SPF krim semakin meningkat. Formulasi dengan kandungan ekstrak licorice 3% menghasilkan aktivitas antioksidan terkuat dengan nilai IC50 sebesar 91,21 ppm (kategori kuat) dan nilai SPF tertinggi sebesar 12,63 (kategori proteksi maksimal).
Research
has been conducted on the formulation of tamanu oil-based creams with varying
concentrations of licorice extract, along with tests on physical stability,
antioxidant activity, and UV protection. The objectives of this study were to
formulate and characterize tamanu oil-based cream preparations, investigate the
effect of varying licorice extract concentrations on the physical stability of
the cream, and determine the antioxidant activity and Sun Protection Factor
(SPF) values of tamanu oil-based creams with different licorice extract
concentrations. The study began with an analysis of tamanu oil
characteristics, including moisture content, free fatty acids, and peroxide
value. Cream formulations were prepared without licorice extract and with the
addition of licorice extract at concentrations of 1%, 2%, and 3%. The physical
stability parameters of the cream formulations included organoleptic tests, pH,
homogeneity, spreadability, phase separation, droplet size, and emulsion type.
Antioxidant activity and SPF values were measured using UV-Vis
spectrophotometry.
The
results showed that the addition of licorice extract influenced the physical
stability of the cream. Increasing the licorice extract concentration decreased
the pH, spreadability, and droplet size of the cream formulations. Meanwhile,
the antioxidant activity and SPF values of the cream increased. The formulation
containing 3% licorice extract exhibited the strongest antioxidant activity,
with an IC50 value of 91.21 ppm (classified as strong), and the
highest SPF value of 12.63 (classified as maximum protection).
Kata Kunci : antioksidan, krim, licorice, minyak tamanu, SPF
