THE RELATIONSHIP BETWEEN SEVERE COVID PREDICTION ESTIMATE (SCOPE) SCORE AND MORTALITY IN SEVERE AND CRITICAL COVID-19 PATIENT

Farhan Maheswara, Heni Retnowulan, Rizka Humardewayanti, Ayu Paramaiswari

2025 | Skripsi | PENDIDIKAN DOKTER

Background: The SCOPE score is used to predict the severity of COVID-19. It is made up of D-dimer, CRP, ferritin, and IL-6. A higher SCOPE score is associated with a higher mortality rate. The mortality rate here is calculated within 14 days of hospitalization from admission to the emergency room in severe and critical adult COVID-19 patients. This research will examine the relationship between Severe COVID Prediction Estimate (SCOPE) score and mortality in Severe and Critical COVID-19 Patients based on evaluating authorized data released by WHO, Kemenkes RI, and RSUP dr. Sardjito.

 Objectives: Analyzing the relationship between Severe COVID Prediction Estimate (SCOPE) score and mortality in Severe and Critical COVID-19 Patients.

Method: In this study, I used a retrospective cohort study. The research population consisted of adult COVID-19 patients with severe and critical conditions at Sardjito Hospital in 2021. The independent variable is the Severe COVID Prediction Estimate (SCOPE) score, and the dependent variable is mortality within 14 days.

Result: This research shows, there is a greater chance of severe respiratory failure or death with a higher SCOPE score and a higher level of biomarkers. This study results is different from the cohort research about the use of SCOPE score as a clinical predictor of COVID-19 progression by Bourboulis (Bourboulis et al, 2022). This current research shows that patients with SCOPE score of >11 have a higher risk of mortality compared to patients with SCOPE score of <11>6 versus <6>
 Conclusion: There is Relationship between Severe COVID Prediction Estimate (SCOPE) score (>11) and mortality (RR 1.775, 95% CI 1.583-8.608) in Severe and Critical COVID-19 Patients.

 Key Words: Severe and critical COVID-19 - SCOPE score - Mortality - Retrospective cohort study 

Background: The SCOPE score is used to predict the severity of COVID-19. It is made up of D-dimer, CRP, ferritin, and IL-6. A higher SCOPE score is associated with a higher mortality rate. The mortality rate here is calculated within 14 days of hospitalization from admission to the emergency room in severe and critical adult COVID-19 patients. This research will examine the relationship between Severe COVID Prediction Estimate (SCOPE) score and mortality in Severe and Critical COVID-19 Patients based on evaluating authorized data released by WHO, Kemenkes RI, and RSUP dr. Sardjito.

 Objectives: Analyzing the relationship between Severe COVID Prediction Estimate (SCOPE) score and mortality in Severe and Critical COVID-19 Patients.

Method: In this study, I used a retrospective cohort study. The research population consisted of adult COVID-19 patients with severe and critical conditions at Sardjito Hospital in 2021. The independent variable is the Severe COVID Prediction Estimate (SCOPE) score, and the dependent variable is mortality within 14 days.

Result: This research shows, there is a greater chance of severe respiratory failure or death with a higher SCOPE score and a higher level of biomarkers. This study results is different from the cohort research about the use of SCOPE score as a clinical predictor of COVID-19 progression by Bourboulis (Bourboulis et al, 2022). This current research shows that patients with SCOPE score of >11 have a higher risk of mortality compared to patients with SCOPE score of <11>6 versus <6>
 Conclusion: There is Relationship between Severe COVID Prediction Estimate (SCOPE) score (>11) and mortality (RR 1.775, 95% CI 1.583-8.608) in Severe and Critical COVID-19 Patients.

 Key Words: Severe and critical COVID-19 - SCOPE score - Mortality - Retrospective cohort study 

Kata Kunci : Severe and critical COVID-19, SCOPE score, Mortality, Retrospective cohort study