Korelasi Antara Volume dan Lokasi Intracerebral Hemorrhage dengan Kejadian Herniasi Subfalcine pada Pasien Non-Trauma

Milda Khoiriana, dr. Yana Supriatna, Ph.D., Sp.Rad(K)RI.; dr. Sri Retna Dwidanarti, Sp.Rad(K) Onk

2024 | Tesis | S2 Kedokteran Klinik

Latar Belakang: Intracerebral hemorrhage (ICH) memiliki angka morbiditas dan mortalitas tinggi di seluruh dunia. Salah satu cedera sekunder yang muncul akibat ICH adalah herniasi serebri, khususnya hernia subfalcine. Beberapa penelitian sebelumnya telah melaporkan temuan hernia subfalcine pada beberapa kasus ICH.

Tujuan: Mengetahui korelasi antara lokasi dan volume intracerebral hemorrhage  dengan derajat hernia subfalcine pada kasus perdarahan intraserebral non trauma

Metode: Penelitian analitik observasional dengan desain cross sectional. Data penelitian diperoleh secara retrospektif berdasarkan data sekunder hasil pemeriksaan CT scan kepala. Dilakukan analisis korelatif antara lokasi dan volume intracerebral hemorrhage dengan derajat hernia subfalcine.

Hasil: Sebanyak 50 orang disertakan dalam penelitian ini, mayoritas berjenis kelamin laki-laki (52,0%), berusia 51-65 tahun (42,0%), tidak merokok (56,0%), tidak mengalami diabetes (82,0%), mengalami hipertensi (66,0%), tidak mengalami dislipidemia (80,0%), mengalami ICH dengan etiologi mikroangiopati hipertensi (54,0%), mengalami perdarahan intrakranial lain berupa SAH (32,0%), dan mengalami ICH di area lobar (58,0%). Tidak terdapat korelasi yang signifikan antara lokasi ICH dengan derajat hernia subfalcine (p > 0,05), sedangkan terdapat korelasi yang signifikan antara volume ICH dengan derajat hernia subfalcine (p < 0 xss=removed>

Kesimpulan: Terdapat korelasi yang kuat antara volume intracerebral hemorrhage dengan derajat hernia subfalcine pada kasus perdarahan intraserebral non trauma. Semakin besar volume ICH, semakin berat derajat keparahan herniasi subfalcine.

Background: Intracerebral hemorrhage (ICH) has high morbidity and mortality rates worldwide. One of the secondary injuries that occurs due to ICH is cerebral herniation, especially subfalcine hernia. Several previous studies have reported findings of subfalcine hernia in several cases of ICH.

Objective: To determine the correlation between the location and volume of intracerebral hemorrhage with the degree of subfalcine hernia in cases of non- traumatic intracerebral hemorrhage

Method: Observational analytical study with a cross-sectional design. The research data were obtained retrospectively based on secondary data from head CT scans. A correlative analysis was performed between the location and volume of intracerebral hemorrhage with the degree of subfalcine hernia.

Results: A total of 50 people were included in this study, the majority were male (52.0%), aged 51-65 years (42.0%), non-smokers (56.0%), non-diabetics (82.0%), 0%), hypertension (66.0%), non-dyslipidemia (80.0%), experienced ICH with hypertensive microangiopathy etiology (54.0%), experienced other intracranial hemorrhage in the form of SAH (32.0%), and experienced ICH in the lobar area (58.0%). There was no significant correlation between the location of ICH and the degree of subfalcine hernia (p> 0.05), while there was a significant correlation between the volume of ICH and the degree of subfalcine hernia (p < 0 r =0.752).>

Conclusion: There is a strong correlation between the volume of intracerebral hemorrhage and the degree of subfalcine hernia in cases of non-traumatic intracerebral hemorrhage. The greater the volume of ICH, the more severe the severity of subfalcine herniation.

Kata Kunci : intracerebral hemorrhage; hernia subfalcine; CT-scan