Hubungan Indeks Massa Tubuh Dengan Perbaikan Kreatinin Pasien Pascatransplantasi Ginjal
Azwar Hashfi, dr. Tanaya Ghinorawa, Sp.U(K); Dr.dr. Indrawarman, Sp.U(K)
2024 | Tesis-Spesialis | SP UROLOGI
Latar Belakang: Indeks
Massa Tubuh (IMT) yang tinggi dapat menjadi kontraindikasi untuk menerima
prosedur transplantasi ginjal. Kriteria kelayakan transplantasi berdasarkan
ambang BMI dapat bervariasi antar pusat transplantasi. Dibandingkan dengan
pasien IMT yang normal, pasien obesitas mempunyai akses yang lebih kecil
terhadap layanan transplantasi ginjal. Beberapa pusat transplantasi ginjal juga
menyarankan pasien obesitas untuk menurunkan berat badan sebelum
mempertimbangkan kelayakan untuk prosedur transplantasi.
Penelitian ini bertujuan untuk mengetahui hubungan
antara IMT pasien resipien ginjal dan perbaikan kadar kreatinin serum pascatransplantasi
ginjal. Hipotesis penulis adalah hubungan antara tinggi ataupun rendahnya IMT
mempunyai pengaruh yang berbeda pada populasi penerima transplantasi ginjal.
Metode: Studi potong lintang retrospektif dilaksanakan. Populasi penelitian
adalah pasien-pasien yang menjalani transplantasi ginjal di RSUP Dr. Sardjito.
Populasi terjangkau adalah pasien-pasien yang menjalani transplantasi ginjal di
RSUP Dr Sardjito pada rentang tahun 2018-2022.
Hasil: Diperoleh 51 sampel dengan rincian 40 pasien laki-laki (78,4%) dan 11
pasien perempuan (21,6%). Pasien termuda berusia 12 tahun, sedangkan pasien tertua
berusia 65 tahun dengan rerata usia pasien adalah 38,06 tahun. Sebanyak tujuh pasien
(13,7%) tergolong BMI rendah, 24 pasien (47,1%) tergolong BMI normal, 13 pasien
(25,5%) memiliki BMI berlebihan, dan tujuh pasien (13,7%) memiliki BMI
obesitas. Uji korelasi menggunakan tes Pearson menunjukkan terdapat korelasi
yang lemah antara Indeks Massa Tubuh (IMT) dengan kadar kreatinin serum pada
hari ketujuh pascatransplantasi ginjal.
Kesimpulan: Indeks Massa Tubuh (IMT) pasien resipien ginjal dan kadar kreatinin darah pascatransplantasi memiliki korelasi yang lemah.
Introduction: A high Body Mass Index (BMI) is
often used as a contraindication to receive a renal transplant procedure.
Transplant eligibility criteria based on BMI thresholds may vary between
transplant centers. Compared with normal BMI patients, obese patients have less
access to kidney transplantation. Some transplant centers also advise obese
patients to lose weight before considering eligibility for a transplant
procedure.
This
study sought to determine the relationship between BMI in kidney transplant
recipient patients and improvements in serum creatinine levels after transplantation.
The authors' hypothesis is that the association between high and low BMI levels
has different effects in the population of kidney transplant recipients.
Material
and Method:
Retrospective cross-section study was performed. The study population is
patients underwent kidney transplantation at Dr. Sardjito Hospital. The
reachable population is patients who underwent kidney transplantation at Dr
Sardjito Hospital in 2018-2022.
Results: There were 51 samples obtained
with 40 male patients (78.4%) and 11 female patients (21.6%). The youngest
patient was 12 years old, and the oldest was 65 years old, with an average
patient age of 38.06 years. A total of 7 patients (13.7%) were classified as
low BMI, 24 patients (47.1%) were classified as normal BMI, 13 patients (25
.5%) had an excessive BMI, and 7 patients (13.7%) had a BMI classified as
obese. Correlation test using the Pearson test showed that there was a weak
correlation between Body Mass Index (BMI) and serum creatinine levels on the
seven day after kidney transplantation.
Conclusion: It was found that the Body Mass
Index (BMI) of kidney recipients and post-transplant blood creatinine levels
had a weak correlation.
Kata Kunci : Indeks Massa Tubuh, Kreatinin Darah, Transplantasi Ginjal
