Korelasi Gambaran Radiologi Computed Tomography Karsinoma Hepatoseluler Berdasarkan Barcelona Clinic Liver Cancer Dengan Rasio Trombosit Terhadap Limfosit

Jimmy Indarto Gunawan, Dr. dr. Bagaswoto Poedjomartono, Sp.Rad (K) RI, Sp.KN, M.Kes, FICA.; dr. Wigati Dhamiyati, Sp.Rad (K) Onk Rad

2023 | Tesis-Spesialis | S2 Radiologi

Background :Hepatocellular carcinoma is the fifth leading cause of death from malignant tumors in Asia. The 5-year survival rate for hepatocellular carcinoma is 18%, making it the second most lethal tumor. The ALBI score is one of the determining factors in the prognosis of hepatocellular carcinoma. Objective :The aim of this study was to prove the correlation between the ALBI score and the CT radiological appearance of hepatocellular carcinoma based on BCLC in hepatocellular carcinoma patients. Materials and Methods :This research is an observational analytic study with a retrospective cross-sectional design using secondary data. The research subjects were patients with hepatocellular carcinoma who had undergone a 4-phase abdominal CT-scan examination at the radiology installation of Dr Sardjito General Hospital in the period January 2021 - December 2022, confirmed from the results of anatomical pathology, and had lymphocyte and platelet lab results. The research subjects were taken using the consecutive non-random sampling method. Results :Of the 32 research samples, most of them consisted of men (62.50%), the age range of research subjects was mostly age ? 60 (53%), the highest serum albumin value was < 3 xss=removed xss=removed> 0.05) indicating that the correlation between the CT image of hepatocellular carcinoma and the ALBI score was not statistically significant. Conclusion :There was no statistically significant correlation between the appearance of hepatocellular carcinoma based on the BCLC score and the ALBI score (p = 0.11).

Background :Hepatocellular carcinoma is the fifth leading cause of death from malignant tumors in Asia. The 5-year survival rate for hepatocellular carcinoma is 18%, making it the second most lethal tumor. The ALBI score is one of the determining factors in the prognosis of hepatocellular carcinoma. Objective :The aim of this study was to prove the correlation between the ALBI score and the CT radiological appearance of hepatocellular carcinoma based on BCLC in hepatocellular carcinoma patients. Materials and Methods :This research is an observational analytic study with a retrospective cross-sectional design using secondary data. The research subjects were patients with hepatocellular carcinoma who had undergone a 4-phase abdominal CT-scan examination at the radiology installation of Dr Sardjito General Hospital in the period January 2021 - December 2022, confirmed from the results of anatomical pathology, and had lymphocyte and platelet lab results. The research subjects were taken using the consecutive non-random sampling method. Results :Of the 32 research samples, most of them consisted of men (62.50%), the age range of research subjects was mostly age ? 60 (53%), the highest serum albumin value was < 3 xss=removed xss=removed> 0.05) indicating that the correlation between the CT image of hepatocellular carcinoma and the ALBI score was not statistically significant. Conclusion :There was no statistically significant correlation between the appearance of hepatocellular carcinoma based on the BCLC score and the ALBI score (p = 0.11).

Kata Kunci : Hepatocellular carcinoma, BCLC, ALBI score