Kualitas Hidup Penderita Vitiligo Dalam Kaitannya Dengan Keparahan Penyakit: Kajian Menggunakan Vesplus Dan Imagej

Yulia Eka Irmawati, dr. Fajar Waskito, Sp.KK(K), M.Kes.; dr. Flandiana Yogianti, Ph.D, Sp.DV

2023 | Tesis-Spesialis | S2 Ilmu Kesehatan Kulit dan Kelamin

Latar belakang: Vitiligo merupakan penyakit depigmentasi dapatan yang paling sering dijumpai dan memiliki dampak yang besar terhadap kualitas hidup penderitanya. Banyak pasien vitiligo merasa tertekan dan terstigmatisasi akibat kondisi kulitnya. Derajat keparahan vitiligo berdasarkan luas lesi dilaporkan dapat memengaruhi kualitas hidup pasien. Penilaian kualitas hidup menggunakan instrumen spesifik untuk vitiligo dalam kaitannya dengan derajat keparahan penyakit belum banyak dilakukan di Indonesia. Penelitian ini perlu dilakukan sebagai salah satu pendekatan dalam manajemen vitiligo secara keseluruhan. Tujuan: untuk mengetahui pengaruh derajat keparahan vitiligo terhadap kualitas hidup pasien. Metode: Penelitian ini merupakan penelitian observasional analitik dengan rancangan potong lintang. Subjek diambil dari populasi pasien vitiligo yang berobat ke RSUP Dr. Sardjito. Derajat keparahan lesi vitiligo diukur menggunakan metode VESplus dan ImageJ. Subjek diminta mengisi kuesioner VitiQol untuk penilaian kualitas hidup. Pengaruh derajat keparahan vitiligo terhadap kualitas hidup dianalisis menggunakan regresi linier. Nilai p < 0 xss=removed xss=removed VitiQol =26,121 xss=removed>

Background: Vitiligo is the most common acquired depigmentation disease and highly affects the quality of life. Many people with vitiligo feel depressed and stigmatized because of their skin condition. It has been noted that the quality of life of the patient is impacted by the severity of vitiligo based on the size of the lesion. In Indonesia, there has not been much study done on the relationship between vitiligo severity and the quality of life as measured by specific instruments. This study needs to be done by researchers as one approach in the overall management of vitiligo. Objective: The purpose of this study was to determine the impact of disease severity on the quality of life of patients with vitiligo.Methods: This study was an analytical observational study used a cross-sectional design. Subjects were taken from the population of vitiligo patients who consulted to Dr. Sardjito General Hospital. The severity of vitiligo lesion was measured using the VESplus method and ImageJ. Subjects were asked to fill out a VitiQol questionnaire to assess the quality of life. Linear regression were used to examine the impact of vitiligo severity on quality of life. Statistical significance was defined as p < 0 xss=removed xss=removed xss=removed xss=removed>

Kata Kunci : vitiligo, kualitas hidup, VES, VESplus, ImageJ, VitiQol, vitiligo, quality of life