Korelasi staging FIGO pada MRI pelvis dengan histopatologi karsinoma endometrium

ANGGIE SWARHA PATRIA, DR. dr. Lina Choridah, Sp.Rad (K) PRP; dr. Anita Ekowati, Sp.Rad (K) TR

2023 | Tesis-Spesialis | RADIOLOGI

Tujuan: Penelitian ini bertujuan mengetahui adanya korelasi antara staging FIGO dengan temuan histopatologi melalui MRI pelvis pada penderita karsinoma endometrium. Metode: Penelitian ini merupakan jenis penelitian observasional analitik korelatif dengan desain penelitian cross sectional. Pengambilan data dilakukan secara retrospektif dari data sekunder pasien dengan pengantar klinis curiga karsinoma endometrium yang dilakukan pemeriksaan MRI pelvis di Instalasi Radiologi RSUP Dr. Sardjito Yogyakarta pada bulan Oktober 2017 sampai bulan Agustus 2022. Pengambilan sampel dilakukan secara consecutive non-random sampling. Subjek terpilih sesuai dengan kriteria inklusi dan eksklusi. Dilakukan penilaian staging FIGO pada MRI pelvis dan hasilnya dikorelasikan dengan temuan histopatologi pada pasien. Hasil: Jumlah sampel 25 subjek. Usia didominasi kelompok 56 ���¢�¯�¿�½�¯�¿�½ 65 tahun. Sebagian besar subjek memiliki riwayat status gizi lebih (40%) dan tidak memiliki riwayat diabetes mellitus (76%). Status paritas didominasi multiparitas (72%). Dari analisis Contingency Coefficient, tidak ditemukan hubungan bermakna secara statistik antara staging FIGO melalui MRI pelvis terhadap temuan histopatologi pada pasien karsinoma endometrium. Demikian juga antara variabel lain meliputi usia, status gizi, diabetes mellitus dan status paritas terhadap temuan histopatologis. Kesimpulan: Tipe karsinoma endometrium yang dominan ditemukan dalam penelitian ini memiliki jenis histopatologi dengan agresifitas tinggi dan ditemukan dalam stadium yang lebih lanjut. Tidak ada hubungan yang bermakna antara usia (p = 0,976), status gizi (p = 0,419), diabetes mellitus (p = 0,876) dan status paritas (p = 0,629) dengan temuan histopatologi.

Objective: This study aims to determine the correlation of FIGO staging on pelvis MRI with histopathological findings in endometrial carcinoma patients Method: This was an analytic observational study with a cross-sectional research design. Data collection was carried out retrospectively from secondary data of patients with an introduction to the clinical suspected endometrial carcinoma who underwent a pelvis MRI examination at the Radiology Installation of RSUP Dr. Sardjito Yogyakarta from October 2017 to Agustus 2022. Sampling was carried out using consecutive non-random sampling. Subjects were selected according to the inclusion and exclusion criteria. FIGO staging assessment was carried out with pelvis MRI and the results were correlated with histopathological findings in the patient. Result: The number of samples is 25. The age group was dominated by 56 ���¢�¯�¿�½�¯�¿�½ 65 years (40%). Most of them had a history of excess nutrition (40%) and did not have a history of diabetes mellitus (76%). Parity status is dominated by multiparity (72%). From the Contingency Coefficient analysis, there was no statistically significant relationship was found between FIGO staging on pelvis MRI to histopathological findings in endometrial carcinoma patients. Likewise among other variables including age, nutritional status, diabetes mellitus, and parity status to histopathological findings. Conclusion: The dominant type of endometrial carcinoma found in this study has a histopathological type with high aggressiveness and is found in a more advanced stage. There was no significant relationship between age (p= 0,976), nutritional status (p=0,419), diabetes mellitus (p=0,876) and parity status (p=0,629) to histopathological findings.

Kata Kunci : Staging FIGO, histopatologi, karsinoma endometrium