Analisis Sosiodemografi Dan Kepatuhan Pengobatan Terhadap Outcome Klinik Dan Kualitas Hidup Pasien Diabetes Melitus Tipe 2 Dengan Diabetes Quality Of Life Clinical Trial Questionnaire (DQLCTQ)
ARIE FIRDIAWAN, Dr. Susi Ari Kristina, M.Kes., Apt; Dr. Tri Murti Andayani, Sp.FRS., Apt
2019 | Tesis | MAGISTER FARMASI KLINIKDiabetes melitus merupakan penyakit kronis yang membutuhkan pengobatan jangka panjang dan kompleks dimana kepatuhan penggunaan obat yang tinggi akan menghasilkan outcome klinik yang baik serta dapat meningkatkan kualitas hidup pasien diabetes melitus. Penelitian ini bertujuan untuk menganalisis sosiodemografi dan kepatuhan pengobatan terhadap outcome klinik dan kualitas hidup pasien diabetes mellitus tipe 2 di beberapa Puskesmas Kota Yogyakarta dan Kabupaten Bantul. Penelitian ini menggunakan desain cross sectional dengan total responden 200 pasien yang memenuhi kriteria inklusi dan eksklusi. Data kepatuhan pengobatan pasien diperoleh dengan menggunakan kuisioner medication adherence report scale (MARS 5), data outcome klinik pasien berdasarkan glukosa darah sewaktu/puasa dari rekam medik, data kualitas hidup menggunakan kuisioner diabetes mellitus quality of life clinical trial questinnare (DQLCTQ), data sosio demografi diperoleh dari wawancara dan rekam medik. Analisis hubungan sosiodemografi terhadap kepatuhan dan outcome klinik serta kepatuhan terhadap outcome klinik mengunakan analisis Chi square, kemudian analisis perbedaan kualitas hidup terhadap sosiodemografi dan kepatuhan menggunakan analisis mann-whitney. Dari hasil analisis terhadap 200 pasien memiliki tingkat kepatuhan rendah (57%), outcome klinik belum tercapai (68%), dan rata-rata skor kualitas hidup adalah 71,48; SD± 8,58. Dilihat dari sosisodemografi terdapat hubungan antara status ekonomi dengan outcome klinik (p=0,008; OR=2,386; CI=1,247-4,566) dan terdapat hubungan antara kepatuhan terhadap outcome klinik (p=0,009; 0R=2,211; CI=1,208-4,048). Terdapat perbedaan kualitas hidup berdasarkan tingkat kepatuhan (p=0,016).
Diabetes mellitus is a chronic disease that requires long-term and complex treatment where high compliance with drug use will produce good clinical outcomes and can improve the quality of life for patients with diabetes mellitus. This study aimed to analyze sociodemography and treatment adherence to clinical outcomes and the quality of life of patients with type 2 diabetes mellitus in several Yogyakarta City Health Centers and Bantul District. This study used a cross sectional design with a total of 200 respondents who met the inclusion and exclusion criteria. Data on patient medication adherence was obtained by using medication adherence report scale questionnaire (MARS 5), patient clinical outcome data based on blood glucose during from medical records, quality of life data using questionnaires diabetes mellitus quality of life clinical trial questinnare (DQLCTQ), social data demographics were obtained from interviews and medical records. Analysis of sociodemographic relationships on adherence and clinical outcome and adherence to clinical outcomes using Chi square analysis, then analysis of differences in quality of life on sociodemography and compliance using mann-whitney analysis. From the results of the analysis of 200 patients who had a low level of adherence (57%), the clinical outcome had not been reached (68%), and the average quality of life score was 71.48; SD± 8.58. Judging from the sausage demographic there is a relationship between economic status and clinical outcome (p = 0.008; OR = 2.386 CI=1,247-4,566) and there is a relationship between adherence to clinical outcomes (p = 0.009; 0R = 2.211 CI=1,208-4,048). There were differences in quality of life based on the level of compliance (p = 0.016)
Kata Kunci : Diabetes melitus tipe 2, kepatuhan pengobatan, outcome klinik, kualitas hidup
