SINTESIS DAN UJI AKTIVITAS TURUNAN SENYAWA DISIANOVINIL DAN 1H-TETRAZOL DARI BENZALDEHIDA SEBAGAI SENSOR KOLORIMETRI ANION; SYNTHESIS AND ACTIVITY TEST OF DICYANOVINIL AND 1H-TETRAZOL DERIVATIVES FROM BENZALDEHYDE AS A COLORIMETRIC ANION SENSOR

SUMARWATI, MELI, Bambang Purwono

2016 | Skripsi | FMIPA

Synthesis and activity of dicyanovinil and 1H-tetrazol derivatives from benzaldehyde as a colorimetric anion sensor have been examined. The compound 2-benzylidenemalononitrile (1) have been obtained by the Knoevenagel condensation reaction between benzaldehyde with malononitrile and gave 53,46% yield. The compound 3-phenyl-2-(1H-tetrazole-5-yl)acrylonitrile (2) have been obtained by the 1,3-dipolar cycloaddition reactions of the compound 1 with natrium azide and gave 29,7% yield. The identification of products were done by melting point determination, spectroscopy IR and GC-MS chromatography. Anion sensing properties were determined by using visual color change and UV-vis spectroscopy. The activity test of anion sensor showed that compound 1 resulted color change on addition of CN- and I- in solvent DMSO. The compound 2 indicated high sensitivity and selectivity for F- over other anions (Cl-, Br-, I-, CN-, SO32-, SO42- dan H2PO4-). The compound 1 and 2 showed hypsochromic shift in UV-Vis spectra. The analysis of UV-Vis spectra of compound 1 displayed the shift of ?max = 560 nm to ?max = 510 nm on detection for CN- and to ?max=500 nm on detection for I-. Both anions gave an obvious color change from purple to yellow. Compound 2 also indicated the shift of ?max = 310 nm to ?max = 300 nm on detection for F- with a limit of detection was 2,49 × 10-4 M. This anion gave an obvious color change from yellow to colorless.

Kata Kunci : anion sensors, colorimetric, hypsochromic shift