Hubungan antara lokasi tumor dan bentuk tumor colorectal pada pemeriksaan barium enema dengan gejala klinis pada pasien carcinoma colorectal

KANIYA, Tantri Dwi, Dr. H. Bagaswoto P., SpRad.,SpKN.,M.Kes

2007 | Tesis | PPDS I Radiologi

Latar Belakang : Pasien carcinoma colorectal biasanya datang kepada dokter dalam fase simptomatis. Gambaran klinis tergantung pada ukuran, bentuk dan lokasi tumor. Tujuan : mengetahui hubungan antara lokasi tumor dan bentuk tumor colorectal pada pemeriksaan barium enema dengan gejala klinis pada pasien carcinoma colorectal. Bahan dan Cara : Penelitian cross sectional pada pasien carcinoma colorectal yang menjalani pemeriksaan barium enema di Instalasi Radiologi RS Dr Sardjito Yogyakarta pada periode Januari 2003 sampai Desember 2005. Dikumpulkan data mengenai gejala klinis, lokasi tumor dan bentuk tumor pada pemeriksaan barium enema. Seluruh data dianalisis dengan Chi-square dan Regresi linier. Hasil : Terdapat 122 pasien yang memenuhi kriteria inklusi dan eksklusi sebagai subyek penelitian. Terdapat perbedaan bermakna antara lokasi tumor dengan gejala klinis berupa anemia, teraba massa abdomen, penurunan berat badan, gangguan buang air besar, perdarahan per rectal dan nyeri perut. Terdapat perbedaan bermakna antara bentuk tumor dengan gejala klinis anemia, teraba massa abdomen, penurunan berat badan dan perubahan pola buang air besar. Terdapat hubungan bermakna antara lokasi tumor dengan gejala klinis berupa perdarahan per-rektal dan teraba massa abdomen. Terdapat hubungan bermakna antara bentuk tumor dengan gejala klinis berupa perubahan pola buang air besar. Kesimpulan : Terdapat hubungan bermakna antara lokasi tumor di rectum dengan gejala klinis perdarahan per-rectal (signifikansi 0,003) dan antara lokasi tumor di colon ascenden dan colon transversum dengan gejala klinis teraba massa abdomen (signifikansi 0,008). Sedangkan bentuk tumor annular berhubungan bermakna dengan gejala klinis berupa perubahan pola buang air besar (signifikansi 0,024).

Background : Patient with colorectal cancer usually visit the doctors after they complaint for something. The clinical symptoms are varied depend upon the shape, size and location of the tumors. Material and methods : A cross-sectional study was conducted with subjects were colorectal cancer patient who underwent barium enema examination at Radiology Units of Dr Sardjito General Hospital Yogyakarta, in a period of January 2003 until December 2005. We collected the clinical symptoms, location and shape of the tumors from barium enema examination. All the examination results were analized by Chi-Square and Linier Regression Test Results : We evaluated 122 patients who fulfil inclusion and exclusion criteria as a subject in this study. There were significantly difference between location of tumor and clinical symptoms for anemia, palpable mass, decrease of weight, change of bowel habits, bloody stool and abdominal pain. There were significantly difference between shape of tumor and clinical symptoms for anemia, palpable mass, decrease of weight and change of bowel habits. There were significantly conection between location of tumor and clinical symptoms for palpable mass and bloody stool. There was significantly conection between shape of tumor and clinical symptom change of bowel habits. Conclusions : There were significantly conection between tumor in rectum and bloody stool (sig. 0,003), between tumor in ascending colon, transverse colon and palpable mass (sig. 0,008), There was significantly connection between annular shape and change of bowel habits (sig. 0,024)

Kata Kunci : Carcinoma Colorectal,Barium Enema,colorectal cancer, clinical symptom, location, shape of tumor