ANGKA NORMAL KETEBALAN NERVE FIBER LAYER PERIPAPIL DAN MAKULA PADA ANAK SEHAT DI YOGYAKARTA

ALVIN HENDRYANTO, dr. Angela Nurini Agni, Sp.M (K), M.Kes.; dr. Agus Supartoto, Sp.M(K).

2016 | Tesis-Spesialis | SP ILMU PENYAKIT MATA

Pendahuluan: Pemeriksaan OCT (Optical Coherence Tomography) adalah salah satu pemeriksaan penunjang di bidang ophthalmology. Sebagai alat ukur OCT telah menyediakan angka rujukan normal, namun angka tersebut hanya diperuntukkan bagi penderita dengan usia diatas 18 tahun, sedangkan pada beberapa penelitian menunjukkan perbedaan ketebalan normal pada dewasa dan anak, sehingga angka normal populasi dewasa tidak dapat digunakan sebagai panduan pada pasien anak. Beberapa penelitian rujukan angka normal hasil pemeriksaan OCT telah dilakukan dibeberapa tempat. Telah ada penelitian yang menetapkan hasil normal pada anak di populasi ASIA di Cina dan Hongkong, namun apakah hasilnya dapat langsung diaplikasikan di Indonesia. Tujuan penelitian: Mendapatkan gambaran hasil pemeriksaan OCT RNFL dan makula pada anak sehat di Yogyakarta Indonesia Rancangan penelitian: Penelitian ini menggunakan rancangan cross-sectional Cara penelitian: Sejumlah usia 7 - 12 tahun dilakukan pemeriksaan ketebalan RNFL dengan OCT (SD OCT).

Purpose: To describe normal reference value for peripapilary retinal nerve fiber layer (RNFL) and macular thickness (MT) in Indonesian children Methods: This was a cross-sectional study of children aged 7 to 12 years. We included healthy children whose visual acuity were 6/6 without or with spherical correction up to -2.0D, no retinal or optic nerve abnormalities, ocular trauma, glaucoma or premature birth. Measurement of RNFL thickness and MT was done using Optovue RTvue-100, with scan speedand auto-alignment method, as the default on the machine. We excluded OCT results with signal strength less than 7. Multiple linear regression was used to estimate age and gender effect to RNFL thickness and MT. Results: There were 766 eyes (383 chilren, 197 boys and 166 girls) included in this study. The median age of participants was 9,45 + 1,654. The average of overall RNFL thickness was 105-139 mcgm (superior 105-139 mcgm, inferior 134-186 mcgm, nasal 63-108 mcgm and temporal 64.2-107 mcgm). For MT, the average of foveal thickness was 207-264.8 mcgm, parafovea 287-330 mcgm (superior 292.2-334.8 mcgm, inferior 289.2-332 mcgm, nasal 288-336 mcgm, temporal 278-322 mcgm), perifovea273.2-311 mcgm (superior 275-313 mcgm, inferior 264-304 mcgm, nasal 288-329 mcgm, temporal 261-301 mcgm). Conclucions: Our study demonstrates the values of RNFL thickness and MT macula in normal, healthy children aged 7 to 12 years. These findings can be used as normative reference for diagnosis and evaluation of certain retinal and macular abnormalities.

Kata Kunci : OCT, SD OCT, angka normal makula anak, ketebalan RNFL anak normal, OCT, SD OCT, normative reference, RNFL and macula thickness in normal children