DIS 615.779 Sud i

Isolation and structural elucidation of 5-deazaflavin coenzyme from saccharopolyspora erythraea and its probable involvement in the erythromycin biosynthesis

Penulis

Sudibyo, Retno Sunarminingsih

Pembimbing: Prof.Dr. R.M. Moechammad Samhoedi Reksohadiprodjo, Apt


ABSTRACT : ABSTRAK CHAPTERS I. GENERAL INTRODUCTION 1 . LITERATURE REVIEW 1 A. Microbial Secondary Metabolites 1. Primary and secondary metabolites 2. Fermentation producing secondary metabolites B. Erythromycin 1. Producing microorganisms 2. Chemical structure 3. Physical and chemical properties 4. Biological activity 5. Biosynthesis a. Overview of 6-deoxyerythronolideB biosynthetic pathway b. Biosynthetic mechanism c. Organization of the synthetic genes C. 5-Deazaflavins 1. Producing microorganisms 2. Chemical structures 3. Biosynthesis 4. Chemical and biochemical properties 5. Roles in microbial enzymatic systems a. Roles in redox enzymatic systems b. Roles in the DNA photolyasis system c. Roles in the biosynthesis of Streptomycete origin antibiotics D. Scientific Consideration E. Hypothesis 1 1 DEVELOPMENT OF MEDIA SUITABLE FOR ERYTHROMYCIN 1. PRODUCT1ON BY Sacchnropolyspora erythraea 1. Introduction 2. Methodology 3. Results and discussion 4. Conclusion IV. IDENTIFICATION AND CO-OCCURRENCE STUDY OF ERYTHROMYCIN AND 5-DEAZAFLAVIN PRODUCTIONS IN Saccharopolyspora eryihraea 1. Introduction 2. Methodology

Kata kunci Eritromisin,Biosintesa,Saccharopolyspora Erythraea,Produksi Eritromisin
Program Studi S3 Ilmu Farmasi UGM
No Inventaris c.1 (11/H/98)
Deskripsi xxx, 250 p., bibl., il., 29 cm
Bahasa Inggris
Jenis Disertasi
Penerbit [Yogyakarta] : Universitas Gadjah Mada, 1998
Lokasi Perpustakaan Pusat UGM
File Tulisan Lengkap dapat Dibaca di Ruang Tesis/Disertasi
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