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Dermatophytosis Impact on Blood Profile of Cats

NG, AU DREY, Dr. drh. Soedarmanto Indarjulianto

2016 | Skripsi | S1 KEDOKTERAN HEWAN

Lesi dermatofitosis kucing sulit dibedakan dengan penyakit kulit lain. Kelemahan diagnosa menggunakan lampu ultraviolet adalah kurang sensitif, kultur fungal membutuhkan waktu lama, serta trichogram dan biopsi membutuhkan keahlian khusus. Profil darah kucing mungkin dipengaruhi dermatophytosis. Penelitian ini bertujuan untuk meneliti hubungan dermatophytosis kucing dengan profil darah. Kucing yang menunjukkan dermatitis berpenyakit diperiksa secara fizik, diambil sampel kerokan kulit untuk dikultur pada agar Sabouraud dextrose, diinkubasi pada 25�°C dan diamati setiap hari maksimal selama tiga minggu. Koloni yang diduga dermatofit dikonfirmasi secara morfologi makroskopis dan mikroskopis. Hasil profil darah yang diperiksa secara manual dikomparasi dengan referensi profil darah kucing sehat. Lima kucing yang diperiksa dikonfimasi menderita dermatophytosis (Microsporum canis) berdasarkan gejala klinis dan karakteristik pertumbuhan fungi. Empat kucing yang menderita dermatophytosis menunjukkan jumlah eritrosit yang normal dan satu eritrositosis (20%). Empat ekor kucing (80%) menunjukkan peningkatan protein plasma total, satu ekor (20%) penurunan fibrinogen, satu ekor kucing (20%) eosinofilia, dua ekor (40%) limfopenia, satu ekor (20%) limfositosis, dua ekor (40%) neutrofilia, dan satu ekor kucing (20%) monositosis. Secara keseluruhannya, dua ekor kucing (40%) mengalami leukositosis dan tiga ekor kucing (60%) mempunyai total leukosit normal. Kesimpulannya, peningkatan protein plasma total merupakan perubahan paling konsisten pada kucing penderita dermatofitosis.

Feline dermatophytosis lesions are similar to various dermatoses. Current diagnosis via Woodâ��s lamp illumination lacks sensitivity, fungal culture consumes time whereas trichogram and biopsy requires expertise. Blood profile may be altered in feline dermatophytosis. The aim of this study is to investigate the correlation between feline dermatophytosis and blood profile. Cats with dermatoses were examined clinically, had skin scraped for fungal culture on Sabouraud dextrose agar, incubated at 25�°C and observed daily for a maximum of three weeks. Suspected dermatophyte colonies were confirmed by observing macroscopic and microscopic morphology. Blood profile would be examined manually and the results were compared with reference range of healthy cats. Five cats were confirmed dermatophytic from clinical signs and fungal characteristics. The fungus was identified as Microsporum canis. The five dermatophytic catsâ�� RBC related blood parameters remained normal except one (20%) had erythrocytosis. Four (80%) had elevated total plasma protein and one (20%) had decreased fibrinogen. One (20%) had eosinophillia, two (40%) had lymphopenia, one (20%) had lymphocytosis, two (40%) had neutrophillia and one (20%) had monocytosis. Overall, two (40%) had leukocytosis and three (60%) normal leukocyte numbers. In conclusion, elevated total plasma protein are the most consistent changes in feline dermatophytosis.

Kata Kunci : Feline dermatophytosis, blood, eosinophilia, total plasma protein

  1. S1-2016-340750-abstract.pdf  
  2. S1-2016-340750-bibliography.pdf  
  3. S1-2016-340750-tableofcontent.pdf  
  4. S1-2016-340750-title.pdf